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Farbod Bahreini
Biochemistry
Cell and Molecular Biology
Immunology

Farbod Bahreini

PhD candidate in Immunology with a strong background in biochemistry, molecular biology, and cancer-related research. Experienced in protein analysis, T cell receptor diversity, and enzyme kinetics. Proficient in establishing scientific connections and fostering collaborative research. As a certified peer-reviewer for Elsevier, I bring a critical eye to scientific literature and aim to apply my expertise to drive innovation in academic and industry research settings.

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Main Ph.D. Focus

T Cell Receptor Repertoire

My Ph.D. is focused on understanding the alterations in the Tfh cells receptor repertoire in skin blistering diseases

Nano Particles

As part of my Ph.D., I isolate nano particles derived from cell lines

Research Interests

T Cell Receptor Repertoire

Analyzing the alteration of TCRR in diseases

Protein Biochemistry

I am interested in understanding how protein structures can be recruited as a therapeutic option.

Cancer Biomarker

Part of my research is focused on understanding the role of non coding RNAs and their application in developing biomarkers for the early detection of cancer

Education

2022-present: Ph.D. Candidate, Immunology, University of Luebeck, Luebeck, Germany, Thesis: CD4+ T cell receptor sequences during progression towards experimental pemphigoid Supervisor: Prof. Dr. Kathrin Kalies

2018-2021: M.Sc., Biochemistry, Tarbiat Modares University, Tehran, Iran, Thesis: Investigation of structural, activity, and stability alterations of lactate dehydrogenase in the presence of different additives, Supervisor: Prof. Dr. Khosro Khajeh

2014-2018: B.Sc., Cell and Molecular Biology, Guilan University, Rasht, Iran, Thesis: The relation between miR-559 gene polymorphism and the incidence of breast and gastric cancers, Supervisors: Prof. Dr. Zivar Salehi, Dr. Shirin Shahangian

Academic Background

Bacterial Quorum Sensing: A Double-Edged Sword in Cancer Development
Paniz MI, Tina RL, Farzaneh D, Bahreini F, Rezaei N.
Advanced Biology (Weinh). 2025 Jul 21:e00023.

Oral FcRn-targeted insulin: Challenges and current strategies
Aghakhani A, Bahreini F, Uversky VN, Rezaei N.
Journal of Drug Delivery Science and Technology, 2025.

Meeting Report on “The International Congress on Autoimmune Pre-disease (2024)”
Ohmes J, Mehrpourvan A, Bahreini F, et al.
JID Innovations 5(3), 100342, 2025.

Nanoparticles containing intracellular proteins modulate neutrophil functional and phenotypic heterogeneity
Raudszus L, Bahreini F, Allan S, Kalies K, Caldwell C.
Frontiers in Immunology 15, 1494400, 2025.

Inducing Apoptosis in Acute Myeloid Leukemia; Mechanisms and Limitations
Koolivand Z, Bahreini F, Rayzan E, Rezaei N.
Heliyon 11(1), 2024.

Current Therapeutic Approaches and Promising Perspectives of Using Bioengineered Peptides in Fighting Chemoresistance in Triple-Negative Breast Cancer
Azari M, Bahreini F, Uversky VN, Rezaei N.
Biochemical Pharmacology 210, 115459, 2023.

Clinical whole-exome sequencing analysis reveals a novel missense COL11A1 mutation
Mirtavoos-Mahyari H, Ajami S, Mehrtash A, Marashiyan SM, Bahreini F, et al.
Clinical Case Reports 10(11): e6574, 2022.

Biosynthesis of Copper Nanoparticles Using Aqueous Thymus daenensis (Celak) Flora and Investigation of Its Antifungal Activity
Ebrahimi K, Shir Ovand S, Mohammedi AA, Nabi-Afjadi M, Zalpoor H, Bahreini F.
Journal of Medical Microbiology and Infectious Diseases 10(3): 98–103, 2022.

Analysis of T Cell Repertoires of CD45RO CD4 T Cells in Cohorts of Patients with Bullous Pemphigoid: A Pilot Study
Niebuhr M*, Bahreini F*, Fähnrich A, Bomholt C, Bieber K, Schmidt E, Ibrahim S, Hammers CM, Kalies K.
Frontiers in Immunology 13, 1006941, 2022. (*equal contribution)

Modulation of Tumor Vasculature Network: Key Strategies
Taleb M, Mohammadkhani N, Bahreini F, Ovais M, Nie G.
Small Structures 3(6), 2100164, 2022.

Gallium Components-Based Drug Delivery: A Potential Treatment for COVID-19
Torabi S, Bahreini F, Rezaei N.
Infectious Disorders-Drug Targets 22(3): 1–3, 2022.

Protocol to Induce Follicular T Helper Cells, Germinal Centers, and Skin Lesions in Mouse Models for Skin Blistering Diseases
Bahreini F, Niebuhr M, Belde J, Bieber K, Westermann J, Kalies K.
Bio-protocol 12(10): e4414, 2022.

Protocol to Isolate Germinal Centers by Laser Microdissection
Bahreini F, Niebuhr M, Belde J, Westermann J, Kalies K.
Bio-protocol 12(11): e4431, 2022.

MicroRNAs and Diabetes Mellitus Type 1
Bahreini F, Rayzan E, Rezaei N.
Current Diabetes Reviews 18(2): 1–8, 2022.

The Role of Noncoding RNAs in Pituitary Adenoma
Bahreini F, Jabbari P, Gossing W, Aziziyan F, Frohme M, Rezaei N.
Epigenomics 13(17): 1421–1437, 2021.

microRNA-Related Single-Nucleotide Polymorphisms and Breast Cancer
Bahreini F, Rayzan E, Rezaei N.
Journal of Cellular Physiology 236(3): 1593–1605, 2021.

The Role of Angiotensin-Converting Enzyme 2 in COVID-19 Induced Lung Injury
Torabi S, Bahreini F, Rezaei N.
Acta Bio Medica: Atenei Parmensis 91(4): e2020142, 2020.

miR-559 Polymorphism rs58450758 is Linked to Breast Cancer
Bahreini F, Ramezani S, Shahangian SS, Salehi Z, Mashayekhi F.
British Journal of Biomedical Science 77(1): 29–34, 2020.

  1. Bahreini F, Rezaei N. The role of microRNAs in chemoresistance. Handbook of Cancer and Immunology. DOI: 10.1007/978-3-030-80962-1_336-1 

Reviewer for

Heliyon

Cancer Genetics

Archives of Community Medicine and Public Health

SCIOLBiomedicine

Archives of Pathology and Clinical Research

PeerJ

  • International congress on autoimmune pre-disease-2024

 

Poster title: T Cell Receptor Repertoire Analysis During the Pathogenesis of the Autoimmune Skin Blistering Disease Epidermolysis Bullosa Acquisita

 

  • Conference: 50th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF)-2024

 

Poster title: T Cell Receptor Repertoire Analysis During the Pathogenesis of the Autoimmune Skin Blistering Disease Epidermolysis Bullosa Acquisita

 

  • Conference: 49th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF)- 2023

 

Poster title: Cell-derived nanoparticles regulate the pro-inflammatory cytokine secretion in the murine macrophage cell line J774A.1

 

  • 4th International & 16th Iranian Genetics Congress-2020

 

Poster title: Investigation of recombinant Lactate Dehydrogenase Expression using SUMO fusion tag

 

  • Conference: 16th National Congress of Biochemistry & 7th International Congress of Biochemistry & Molecular Biology 2020

 

 Poster title: Investigating the effect of natural deep eutectic solvents on lactate dehydrogenase activity and stability

 

  • Conference: Third International and Fifteenth Iranian Genetics Congress-2018

 

Poster title: Correlation between miR-559 gene polymorphism and susceptibility to gastric cancer

 

  • Conference: 3rd international and 11th national biotechnology congress of Islamic Republic of Iran-2019

 

Poster title: In-silico analyses to investigate miR-559 gene polymorphism and incidence of breast cancer

Skills

Next-generation sequencing
Laser microdissection
Cloning
Gene expression
Protein stability
Enzyme kinetics
ELISA
Western Blot
Chromatography
PCR
Real-time PCR
Flow Cytometry
DNA/RNA extraction
Animal Handling (Certified FELASA handler)
ZetaView
Nanosight
Cell Cultures
UV vis spectroscopy
Fluorescence spectroscopy
Recombinant Protein Production
SDS PAGE

GraphPad Prism
FlowJo
MedCalc
Microsoft Office
Excel
PowerPoint
Adobe Photoshop

*R (Intermediate): Analyzed NGS results of T cell receptor repertoire diversity using packages like ggplot2, vegan, dplyr, and immunarch for statistical analysis and visualization.
*C (Intermediate): Developed problem-solving and algorithmic skills through coursework applicable to bioinformatics tasks like data processing and simulations.
*Python (Familiar): Learned data science basics, including data manipulation (pandas), visualization (matplotlib), and introductory machine learning.

Reserch Experience

2022–Present: Research Assistant, Department of Anatomy, University of Lübeck, Germany
-Conducted research on autoimmune skin blistering diseases and mentored students

2019–2021: Research Assistant, Department of Biochemistry, Tarbiat Modares University, Iran
-Focused on hyaluronic acid extraction from rooster comb, including sample preparation and data analysis.

2018–2019: Research Assistant, Department of Biochemistry, Tarbiat Modares University, Iran,
-Worked on cloning and expression of GDNF protein, along with sample preparation and analysis.

As part of my M.Sc. thesis I investigated structural, activity, and stability alterations of lactate dehydrogenase in the presence of different additives at the Department of Biochemistry, Tarbiat Modares University, Iran

2016–2017: Junior Researcher, Department of Biology, Faculty of Sciences, University of Guilan, Rasht, Iran
-Worked on the role of miRNA SNPs on the incidence of breast and gastric cancer.

Affiliations

2022-present Institute of Anatomy, University of Luebeck, Luebeck, Germany

2020- present Network of Immunity in Infection, Malignancy, and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

2018- 2021 Department of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran

2014-2020 Department of Biology, Faculty of Sciences, University of Guilan, Rasht, Iran

Notable Certificates

I am thrilled to share that I have earned the Certificate of Excellence from the Researcher Academy of ELSEVIER by successfully completing the Certified Peer Reviewer Course.

This has been one of commitment and passion for enriching the quality of scientific research through peer review. I look forward to applying the insights and skills gained from this course to contribute meaningfully to the academic community.

A Good Manufacturing Practice (GMP) certificate ensures that products are consistently produced and controlled according to quality standards. It is crucial for ensuring product safety, efficacy, and regulatory compliance in industries such as pharmaceuticals and food.

Having a good scientific practice certificate ensures that researchers adhere to ethical guidelines and maintain the integrity of their work. It is essential for fostering trust, reproducibility, and accountability in scientific research.

The FELASA (Federation of European Laboratory Animal Science Associations) animal handling certificate obtained in Germany ensures that individuals are trained in the ethical and competent handling of laboratory animals. This certification is essential for maintaining high standards of animal welfare, complying with legal regulations, and promoting responsible research practices.

Languages

I am fluent in English, with a strong command of both academic and everyday language. My fluency allows me to engage confidently with global scientific literature, collaborate with international colleagues, and communicate complex ideas effectively. I continuously refine my language skills through regular practice and learning, ensuring my communication remains clear and professional.

I am currently at an A2 level in German and am actively working towards becoming proficient in the language. Through consistent study and practice, I am steadily improving my skills, aiming to reach a high level of fluency. My goal is to be able to communicate effectively in both professional and everyday contexts, and I dedicate time each day to furthering my understanding of German.

As a native speaker of Persian, I am deeply connected to the language and its rich cultural history. My fluency in Persian allows me to communicate naturally and effectively, both in professional and personal contexts, and to appreciate the nuances and expressions that come with being a native speaker.

I am familiar with the Arabic language, allowing me to understand and engage with basic conversations and texts. While I am not fully fluent, I continue to expand my knowledge and deepen my understanding of the language, particularly in a every day context.

Contact

Get in Touch

+491782943569

Luebeck, Germany

farbod_bahreini@yahoo.com

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